NEPASAFE
- Nepafenac 0.1% w/v- a prodrug that converts to Amfenac, a potent COX-1 and COX-2 inhibitor that blocks the synthesis of prostaglandins.
Nepasafe Eye Drops contain Nepafenac 0.1%, a potent non-steroidal anti-inflammatory drug (NSAID) that offers effective relief from post-operative ocular pain and inflammation following cataract surgery and other ophthalmic procedures.
With its unique prodrug design, Nepafenac ensures enhanced corneal penetration, converting to Amfenac inside the eye for sustained anti-inflammatory action and improved patient comfort.
- Powerful Pain Relief – Reduces post-surgical inflammation and discomfort
- Advanced Suspension Technology – Ensures smooth and uniform dosing
- Fast & Long-Lasting Action – Rapid onset with prolonged relief
- Trusted Post-Operative Care – Safe and effective for daily ophthalmic use
Nepafenac is a prodrug that converts to Amfenac, a potent COX-1 and COX-2 inhibitor that blocks the synthesis of prostaglandins, the primary mediators of ocular inflammation and pain.
This mechanism provides targeted anti-inflammatory relief, reducing post-operative discomfort and enhancing visual recovery.
Prodrug Advantage: Converts to active Amfenac only inside ocular tissues — minimizes surface irritation.
Potent Anti-Inflammatory Action: Reduces pain, redness, and swelling effectively.
Excellent Ocular Tolerance: Gentle on the eye with minimal stinging or burning.
Enhanced Penetration: Reaches posterior ocular tissues for optimal efficacy.
Post-operative pain and inflammation following cataract or refractive surgery
Ocular discomfort due to trauma or inflammation
Prophylaxis and treatment of ocular inflammation
For ophthalmic use only.
Shake well before use.
Avoid touching the dropper tip to any surface.
Use with caution in patients with bleeding disorders or those using other NSAIDs.
Discontinue use if signs of allergic reaction (itching, redness, swelling) occur.
Not recommended for use while wearing contact lenses.
Store below 25°C; protect from light.
Keep out of reach of children.
Temporary eye irritation or discomfort
Mild redness or watering
Sensitivity to light
Rarely: corneal epithelial breakdown (with prolonged use)
Consult a doctor if symptoms persist or worsen.
Instill 1 drop into the affected eye(s) 3 times daily, beginning 1 day before surgery and continuing for up to 2 weeks post-surgery or as directed by the physician.
Shake well before use.
Disclaimer:
For the use of a Registered Medical Practitioner or Hospital only. Nepasafe Eye Drops should be used under medical supervision. Information provided is intended for healthcare professionals.